| Gene Information | |
|---|---|
| Gene Name | COL22A1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1626 |
| Protein Names | Collagen alpha-1(XXII) chain |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000169436 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q8NFW1 |
| Gene Card | COL22A1 |
| Uniprot ID | Q8NFW1 |
| Pfam | PF01391; PF00092 |
| In ASD | no |
| Allosteric Prediction | no (-0.941661442) |
| Ortholog in Animals | Alpaca_ COL22A1 ( ortholog_one2one ) Dog_ COL22A1 ( ortholog_one2one ) GuineaPig_ COL22A1 ( ortholog_one2one ) Macaque_ COL22A1 ( ortholog_one2one ) Pig_ COL22A1 ( ortholog_one2one ) |
| Ohnologs | COL19A1, COL9A1, COL21A1, COL4A3, COL24A1 |
| Paralogs | COL9A2, COLQ, COL4A1, COL17A1, COL1A1, EDA, COL11A1, COL15A1, COL9A3, COL26A1, COL13A1, COL7A1, COL16A1, COL5A1, COL25A1, COL3A1, COL6A2, COL5A3, COL27A1, COL1A2, COL24A1, COL5A2, COL18A1, COL9A1, COL23A1, COL2A1, COL4A2, COL20A1, COL4A4, COL4A6, COL28A1, COL11A2, COL21A1, COL6A1, EMID1, COL4A5, COL4A3 |
| Tissue | adrenal.gland, pituitary.gland |
| Tissue Specificity | Restrictive expression is observed at tissue junctions such as the myotendinous junction in skeletal and heart muscle, the articular cartilage-synovial fluid junction, or the border between the anagen hair follicle and the dermis in the skin. It is deposited in the basement membrane zone of the myotendinous junction and the hair follicle and associated with the extrafibrillar matrix in cartilage. {ECO:0000269|PubMed:15016833}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs2292927 rs10111520 rs4909444 |
| Subcellular location [CC] | Secreted, extracellular space, extracellular matrix. Cytoplasm {ECO:0000250}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |