| Gene Information | |
|---|---|
| Gene Name | SEPTIN1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 372 |
| Protein Names | Septin-1 (LARP) (Peanut-like protein 3) (Serologically defined breast cancer antigen NY-BR-24) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1292 ( ENSG00000180096 ) |
| Evolutionary Stage | Opisthokonta |
| AlphaFoldDB | Q8WYJ6 |
| Gene Card | SEPTIN1 |
| Uniprot ID | Q8WYJ6 |
| Pfam | PF00735 |
| In ASD | no |
| Allosteric Prediction | no (-0.699907482) |
| Ortholog in Animals | Alpaca_ SEPTIN1 ( ortholog_one2one ) Dog_ SEPTIN1 ( ortholog_one2one ) GuineaPig_ SEPTIN1 ( ortholog_one2one ) Mouse_ Septin1 ( ortholog_one2one ) Pig_ SEPTIN1 ( ortholog_one2one ) Rat_ Septin1 ( ortholog_one2one ) Rabbit_ SEPTIN1 ( ortholog_one2one ) |
| Ohnologs | SEPTIN4, SEPTIN5, SEPTIN7, SEPTIN7P2 |
| Paralogs | SEPTIN11, SEPTIN8, SEPTIN12, SEPTIN10, SEPTIN9, TMEM250, SEPTIN3, SEPTIN7, SEPTIN6, SEPTIN5, SEPTIN2, SEPTIN14 |
| Tissue | spleen |
| Tissue Specificity | Expressed at high levels in lymphoid and hematopoietic tissues. {ECO:0000269|PubMed:15915442}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 6WBE (X-ray 2.10A ) |
| DBSNP | rs34518080 |
| Subcellular location [CC] | Cytoplasm {ECO:0000250}. Cytoplasm, cytoskeleton {ECO:0000250}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Midbody. Note=Remains at the centrosomes and the nearby microtubules throughout mitosis. Localizes to the midbody during cytokinesis. |
| Mouse PG classification | NA |
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