| Gene Information | |
|---|---|
| Gene Name | SRR |
| Organism | Homo sapiens (Human) |
| Gene Length | 340 |
| Protein Names | Serine racemase (EC 5.1.1.18) (D-serine ammonia-lyase) (D-serine dehydratase) (EC 4.3.1.18) (L-serine ammonia-lyase) (L-serine dehydratase) (EC 4.3.1.17) |
| Target Name | serine racemase |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000167720 ) |
| Evolutionary Stage | Cellular_organisms |
| AlphaFoldDB | Q9GZT4 |
| Gene Card | SRR |
| Uniprot ID | Q9GZT4 |
| Pfam | PF00291 |
| In ASD | yes |
| Allosteric Prediction | yes (0.702771796) |
| Ortholog in Animals | Alpaca_ SRR ( ortholog_one2one ) GuineaPig_ SRR ( ortholog_one2one ) Macaque_ SRR ( ortholog_one2one ) Mouse_ Srr ( ortholog_one2one ) Pig_ SRR ( ortholog_one2one ) Rat_ Srr ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | THNSL1, SDSL, CBS, SDS, THNSL2 |
| Tissue | NA |
| Tissue Specificity | Brain: expressed at high levels in hippocampus and corpus callosum, intermediate levels in substantia nigra and caudate, and low levels in amygdala, thalamus, and subthalamic nuclei. Expressed in heart, skeletal muscle, kidney and liver. {ECO:0000269|PubMed:15193426}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 3L6B (X-ray 1.50A ) 3L6R (X-ray 1.70A ) 5X2L (X-ray 1.81A ) 6SLH (X-ray 1.89A ) 6ZSP (X-ray 1.60A ) 6ZUJ (X-ray 1.80A ) 7NBC (X-ray 1.71A ) 7NBD (X-ray 1.86A ) 7NBF (X-ray 1.60A ) 7NBG (X-ray 1.53A ) 7NBH (X-ray 1.77A ) |
| DBSNP | NA |
| Subcellular location [CC] | NA |
| Mouse PG classification | NA |
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