| Gene Information | |
|---|---|
| Gene Name | PPM1G |
| Organism | Homo sapiens (Human) |
| Gene Length | 546 |
| Protein Names | Protein phosphatase 1G (EC 3.1.3.16) (Protein phosphatase 1C) (Protein phosphatase 2C isoform gamma) (PP2C-gamma) (Protein phosphatase magnesium-dependent 1 gamma) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | >4290 ( ENSG00000115241 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | O15355 |
| Gene Card | PPM1G |
| Uniprot ID | O15355 |
| Pfam | PF00481 |
| In ASD | no |
| Allosteric Prediction | no (-0.162909167) |
| Ortholog in Animals | Alpaca_ PPM1G ( ortholog_one2one ) Dog_ PPM1G ( ortholog_one2one ) GuineaPig_ PPM1G ( ortholog_one2one ) Macaque_ PPM1G ( ortholog_one2one ) Mouse_ Ppm1g ( ortholog_one2one ) Pig_ PPM1G ( ortholog_one2one ) Rat_ Ppm1g ( ortholog_one2one ) Rabbit_ PPM1G ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | PDP2, TAB1, ILKAP, PPM1B, PPM1L, PPM1N, PP2D1, PDP1, PPM1A, PPM1D, PPM1E, PPM1H, PPM1J, PPM1M, PPM1F, PPM1K |
| Tissue | NA |
| Tissue Specificity | Widely expressed. Most abundant in testis, skeletal muscle, and heart. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001000(Rat);0.008(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm {ECO:0000305}. Membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}. |
| Mouse PG classification | NA |
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