| Gene Information | |
|---|---|
| Gene Name | SRI |
| Organism | Homo sapiens (Human) |
| Gene Length | 198 |
| Protein Names | Sorcin (22 kDa protein) (CP-22) (CP22) (V19) |
| Target Name | sorcin |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000075142 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | P30626 |
| Gene Card | SRI |
| Uniprot ID | P30626 |
| Pfam | PF13405; PF13833 |
| In ASD | no |
| Allosteric Prediction | yes (0.011203987) |
| Ortholog in Animals | Alpaca_ SRI ( ortholog_one2one ) Alpaca_ SRI ( ortholog_one2many ) Dog_ SRI ( ortholog_one2one ) GuineaPig_ SRI ( ortholog_one2one ) Macaque_ SRI ( ortholog_one2one ) Mouse_ Sri ( ortholog_one2one ) Pig_ SRI ( ortholog_one2one ) Rat_ Sri ( ortholog_one2many ) |
| Ohnologs | GCA |
| Paralogs | CAPN1, PEF1, CAPN9, PDCD6, CAPN2, CAPN5, CAPN14, CAPN15, CAPN7, ADGB, CAPN6, CAPN8, CAPN3, CAPN12, CAPNS2, CAPN11, CAPN13, CAPNS1, CAPN10, GCA |
| Tissue | NA |
| Tissue Specificity | Detected in cardiac myocytes. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1JUO (X-ray 2.20A ) 2JC2 (X-ray 2.50A ) 4U8D (X-ray 2.30A ) 4UPG (X-ray 2.10A ) 4USL (X-ray 1.65A ) 5MRA (X-ray 3.74A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm. Sarcoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Note=Relocates to the sarcoplasmic reticulum membrane in response to elevated calcium levels. |
| Mouse PG classification | NA |
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