| Gene Information | |
|---|---|
| Gene Name | SLC6A14 |
| Organism | Homo sapiens (Human) |
| Gene Length | 642 |
| Protein Names | Sodium- and chloride-dependent neutral and basic amino acid transporter B(0+) (Amino acid transporter ATB0+) (Solute carrier family 6 member 14) |
| Target Name | sodium- and chloride-dependent neutral and basic amino acid transporter b(0+) |
| Target Type | NA |
| Gene Age | 55 ( ENSG00000268104 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q9UN76 |
| Gene Card | SLC6A14 |
| Uniprot ID | Q9UN76 |
| Pfam | PF00209 |
| In ASD | no |
| Allosteric Prediction | no (-0.078058541) |
| Ortholog in Animals | Alpaca_ SLC6A14 ( ortholog_one2one ) Macaque_ SLC6A14 ( ortholog_one2one ) Rabbit_ SLC6A14 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | SLC6A20, SLC6A9, SLC6A2, SLC6A18, SLC6A7, SLC6A4, SLC6A16, SLC6A8, SLC6A6, SLC6A15, SLC6A13, SLC6A11, SLC6A19, SLC6A1, SLC6A17, SLC6A12, SLC6A3, SLC6A5 |
| Tissue | lung, salivary.gland, minor.salivary.gland |
| Tissue Specificity | Levels are highest in adult and fetal lung, in trachea and salivary gland. Lower levels detected in mammary gland, stomach and pituitary gland, and very low levels in colon, uterus, prostate and testis. {ECO:0000269|PubMed:10446133}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Membrane {ECO:0000305|PubMed:10446133}; Multi-pass membrane protein {ECO:0000255}. Apical cell membrane {ECO:0000250|UniProtKB:Q9JMA9}; Multi-pass membrane protein {ECO:0000255}. |
| Mouse PG classification | NA |
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