Gene Information
Gene NameSRD5A2L
OrganismHomo sapiens (Human)
Gene Length318
Protein NamesPolyprenol reductase (EC 1.3.1.94) (3-oxo-5-alpha-steroid 4-dehydrogenase 3) (EC 1.3.1.22) (Steroid 5-alpha-reductase 2-like) (Steroid 5-alpha-reductase 3) (S5AR 3) (SR type 3)
Target NameNA
Target TypeNA
Gene AgeNA
Evolutionary StageNA
AlphaFoldDBQ9H8P0
Gene CardSRD5A3
Uniprot IDQ9H8P0
PfamPF02544
In ASDno
Allosteric PredictionNA
Ortholog in AnimalsNA
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityExpressed in preadipocytes (at protein level) (PubMed:26855069). Overexpressed in hormone-refractory prostate cancers (HRPC). Almost no or little expression in normal adult organs. {ECO:0000269|PubMed:17986282, ECO:0000269|PubMed:26855069}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP NA 
Subcellular location [CC]Endoplasmic reticulum membrane {ECO:0000305|PubMed:20637498};
Multi-pass membrane protein {ECO:0000305|PubMed:20637498}.
Mouse PG classificationNA
click here to return to the previous page