| Gene Information | |
|---|---|
| Gene Name | SLC7A2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 658 |
| Protein Names | Cationic amino acid transporter 2 (CAT-2) (CAT2) (Low affinity cationic amino acid transporter 2) (Solute carrier family 7 member 2) |
| Target Name | low affinity cationic amino acid transporter 2 |
| Target Type | NA |
| Gene Age | >4290 ( ENSG00000003989 ) |
| Evolutionary Stage | Cellular_organisms |
| AlphaFoldDB | P52569 |
| Gene Card | SLC7A2 |
| Uniprot ID | P52569 |
| Pfam | PF13520; PF13906 |
| In ASD | no |
| Allosteric Prediction | yes (0.32662064) |
| Ortholog in Animals | Alpaca_ SLC7A2 ( ortholog_one2one ) Dog_ SLC7A2 ( ortholog_one2one ) GuineaPig_ SLC7A2 ( ortholog_one2one ) Macaque_ SLC7A2 ( ortholog_one2one ) Mouse_ Slc7a2 ( ortholog_one2one ) Pig_ SLC7A2 ( ortholog_one2one ) Rat_ Slc7a2 ( ortholog_one2one ) Rabbit_ SLC7A2 ( ortholog_one2one ) |
| Ohnologs | SLC7A1, SLC7A3 |
| Paralogs | SLC7A6, SLC7A10, SLC7A9, SLC7A8, SLC7A11, SLC7A13, SLC7A14, SLC7A7, SLC7A3, SLC7A4, SLC7A1, SLC7A5 |
| Tissue | NA |
| Tissue Specificity | Expressed at high levels in the skeletal muscle, placenta and ovary. Expressed at intermediate levels in the liver and pancreas and at low levels in the kidney and heart. {ECO:0000269|PubMed:8954799}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs12680645 rs1134975 rs62622371 rs1981498 |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:9174363}; Multi-pass membrane protein {ECO:0000269|PubMed:9174363}. |
| Mouse PG classification | NA |
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