| Gene Information | |
|---|---|
| Gene Name | SPY1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 313 |
| Protein Names | Speedy protein A (Rapid inducer of G2/M progression in oocytes A) (RINGO A) (hSpy/Ringo A) (Speedy-1) (Spy1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q5MJ70 |
| Gene Card | SPDYA |
| Uniprot ID | Q5MJ70 |
| Pfam | PF11357 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Highly expressed in testis. Expressed at a low level in wide range of tissues including bone marrow, brain, heart, kidney, colon, liver, placenta, spleen, skeletal muscle, salivary gland, thyroid gland, thymus, trachea and uterus. Expressed at a slightly higher level in adrenal gland, cerebellum, small intestine, lung, prostate and trachea. Expression is cell cycle-dependent, being restricted to cells in G1/S phase. {ECO:0000269|PubMed:11980914, ECO:0000269|PubMed:15611625}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.004323(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 5UQ1 (X-ray 3.20A ) 5UQ2 (X-ray 2.70A ) 5UQ3 (X-ray 3.60A ) 7E34 (X-ray 3.19A ) |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:11980914, ECO:0000269|PubMed:12972555}. |
| Mouse PG classification | NA |
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