| Gene Information | |
|---|---|
| Gene Name | SPAG16 |
| Organism | Homo sapiens (Human) |
| Gene Length | 631 |
| Protein Names | Sperm-associated antigen 16 protein (Pf20 protein homolog) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000144451 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | Q8N0X2 |
| Gene Card | SPAG16 |
| Uniprot ID | Q8N0X2 |
| Pfam | PF00400 |
| In ASD | no |
| Allosteric Prediction | no (-1.014156163) |
| Ortholog in Animals | Alpaca_ SPAG16 ( ortholog_one2one ) Dog_ SPAG16 ( ortholog_one2one ) Macaque_ SPAG16 ( ortholog_one2one ) Mouse_ Spag16 ( ortholog_one2one ) Pig_ SPAG16 ( ortholog_one2one ) Rat_ Spag16 ( ortholog_one2one ) Rabbit_ SPAG16 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Isoform 1 is detected in testis. Isoform 4 is detected in testis and brain, and at lower levels in kidney, heart, pancreas, thyroid, ovary, adrenal gland, spinal cord, trachea and liver. {ECO:0000269|PubMed:11867345, ECO:0000269|PubMed:12391165}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001000(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs10167688 rs2042791 rs12623569 |
| Subcellular location [CC] | Cytoplasm {ECO:0000250|UniProtKB:Q8K450}. Cytoplasm, cytoskeleton, flagellum axoneme {ECO:0000250|UniProtKB:Q8K450}. Cytoplasm, cytoskeleton, cilium axoneme {ECO:0000250|UniProtKB:Q8K450}. Cell projection, cilium, flagellum {ECO:0000250|UniProtKB:Q8K450}. Note=Detected on the sperm flagellum axoneme. Detected in the central apparatus of the axoneme. Colocalizes with SPAG6 on microtubules (By similarity). {ECO:0000250|UniProtKB:Q8K450}. |
| Mouse PG classification | NA |
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