| Gene Information | |
|---|---|
| Gene Name | SPRY3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 288 |
| Protein Names | Protein sprouty homolog 3 (Spry-3) (Sprouty RTK signaling antagonist 3) (Sprouty3) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 886 ( ENSG00000168939 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | O43610 |
| Gene Card | SPRY3 |
| Uniprot ID | O43610 |
| Pfam | PF05210 |
| In ASD | no |
| Allosteric Prediction | no (-0.614969665) |
| Ortholog in Animals | Alpaca_ SPRY3 ( ortholog_one2one ) Dog_ SPRY3 ( ortholog_one2one ) GuineaPig_ SPRY3 ( ortholog_one2one ) Macaque_ SPRY3 ( ortholog_one2one ) Pig_ SPRY3 ( ortholog_one2one ) Rat_ RGD1564382 ( ortholog_one2many ) Rat_ Spry3 ( ortholog_one2many ) Rabbit_ SPRY3 ( ortholog_one2one ) |
| Ohnologs | SPRY2, SPRY1 |
| Paralogs | SPRY2, SPRY1, SPRY4 |
| Tissue | NA |
| Tissue Specificity | Widely expressed; particularly in the fetal tissues. Expressed in the brain with expression the highest in Purkinje cells in the cerebellum (at protein level) (PubMed:26089202). Expressed in the myocardium of the heart (PubMed:30878395). {ECO:0000269|PubMed:26089202, ECO:0000269|PubMed:30878395}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs35474915 |
| Subcellular location [CC] | Cytoplasm. |
| Mouse PG classification | NA |
| click here to return to the previous page | |