Gene Information
Gene NameSPRR4
OrganismHomo sapiens (Human)
Gene Length79
Protein NamesSmall proline-rich protein 4
Target NameNA
Target TypeNA
Gene Age36 ( ENSG00000184148 )
Evolutionary StageMammalia
AlphaFoldDBQ96PI1
Gene CardSPRR4
Uniprot IDQ96PI1
PfamNA
In ASDno
Allosteric Predictionno (-1.384230349)
Ortholog in AnimalsAlpaca_ SPRR4 ( ortholog_one2one )
Mouse_ Sprr4 ( ortholog_one2one )
Rat_ NEWGENE_2324572 ( ortholog_one2one )
OhnologsNA
ParalogsPRR9, LCE1D, LCE1E, LCE1F, SPRR3, C1orf68, SPRR1B, SPRR1A, LCE3B, LCE3C, LCE3A, LCE2C, LCE5A, LCE2D, LCE2A, LCE2B, LELP1, SPRR2G, LCE3D, LCE3E
Tissueskin, suprapubic.skin
Tissue SpecificityNA
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs16834786 
Subcellular location [CC]Cytoplasm. Cytoplasm, cell cortex. Note=Translocates to the cell periphery of keratinocytes and is integrated into both rigid and fragile cornified envelopes.
Mouse PG classificationNA
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