| Gene Information | |
|---|---|
| Gene Name | SFXN2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 322 |
| Protein Names | Sideroflexin-2 |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000156398 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q96NB2 |
| Gene Card | SFXN2 |
| Uniprot ID | Q96NB2 |
| Pfam | PF03820 |
| In ASD | no |
| Allosteric Prediction | no (-1.177678838) |
| Ortholog in Animals | Alpaca_ SFXN2 ( ortholog_one2one ) Dog_ SFXN2 ( ortholog_one2one ) GuineaPig_ SFXN2 ( ortholog_one2one ) Mouse_ Sfxn2 ( ortholog_one2one ) Pig_ SFXN2 ( ortholog_one2one ) Rat_ Sfxn2 ( ortholog_one2one ) Rabbit_ SFXN2 ( ortholog_one2one ) |
| Ohnologs | SFXN1 |
| Paralogs | SFXN3, SFXN1, SFXN4, SFXN5 |
| Tissue | NA |
| Tissue Specificity | Widely expressed, highest levels in kidney, liver, and pancreas. {ECO:0000269|PubMed:12670026}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.033333(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Mitochondrion inner membrane {ECO:0000269|PubMed:30442778}; Multi-pass membrane protein {ECO:0000255}. Mitochondrion outer membrane {ECO:0000269|PubMed:30570704}; Multi-pass membrane protein {ECO:0000255}. |
| Mouse PG classification | NA |
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