Gene Information
Gene NameSPTRX
OrganismHomo sapiens (Human)
Gene Length553
Protein NamesThioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1)
Target NameNA
Target TypeNA
Gene AgeNA
Evolutionary StageNA
AlphaFoldDBQ86VQ3
Gene CardTXNDC2
Uniprot IDQ86VQ3
PfamPF00085
In ASDno
Allosteric PredictionNA
Ortholog in AnimalsNA
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityTestis-specific. Only expressed during spermiogenesis, prominently in round and elongating spermatids. {ECO:0000269|PubMed:11399755}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs11662946  rs2240909  rs11081510  rs2240906  rs17732496  rs17805544 
Subcellular location [CC]Cytoplasm {ECO:0000269|PubMed:11399755}. Note=In ejaculated spermatozoa, it localizes in the caudal region of the head to the end of the principal piece.
Mouse PG classificationNA
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