| Gene Information | |
|---|---|
| Gene Name | SPR |
| Organism | Homo sapiens (Human) |
| Gene Length | 261 |
| Protein Names | Sepiapterin reductase (SPR) (EC 1.1.1.153) |
| Target Name | sepiapterin reductase |
| Target Type | NA |
| Gene Age | 1292 ( ENSG00000116096 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | P35270 |
| Gene Card | SPR |
| Uniprot ID | P35270 |
| Pfam | PF00106 |
| In ASD | no |
| Allosteric Prediction | yes (0.595774792) |
| Ortholog in Animals | Alpaca_ SPR ( ortholog_one2one ) Dog_ SPR ( ortholog_one2one ) GuineaPig_ SPR ( ortholog_one2one ) Macaque_ SPR ( ortholog_one2one ) Mouse_ Spr ( ortholog_one2one ) Pig_ SPR ( ortholog_one2one ) Rat_ RGD1560795 ( ortholog_one2many ) Rat_ Spr ( ortholog_one2many ) Rabbit_ SPR ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1Z6Z (X-ray 2.50A ) 4HWK (X-ray 2.40A ) 4J7U (X-ray 2.44A ) 4J7X (X-ray 2.60A ) 4XWY (X-ray 2.35A ) 4Z3K (X-ray 2.35A ) 6I6C (X-ray 1.72A ) 6I6F (X-ray 1.94A ) 6I6P (X-ray 1.62A ) 6I6T (X-ray 1.79A ) 6I6V (X-ray 1.43A ) 6I79 (X-ray 1.63A ) 6USN (X-ray 2.77A ) 7DSF (X-ray 1.80A ) |
| DBSNP | rs104893665 rs104893666 |
| Subcellular location [CC] | Cytoplasm. |
| Mouse PG classification | NA |
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