| Gene Information | |
|---|---|
| Gene Name | SPP1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 314 |
| Protein Names | Osteopontin (Bone sialoprotein 1) (Nephropontin) (Secreted phosphoprotein 1) (SPP-1) (Urinary stone protein) (Uropontin) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 424 ( ENSG00000118785 ) |
| Evolutionary Stage | Mammalia |
| AlphaFoldDB | P10451 |
| Gene Card | SPP1 |
| Uniprot ID | P10451 |
| Pfam | PF00865 |
| In ASD | no |
| Allosteric Prediction | yes (0.842295595) |
| Ortholog in Animals | Alpaca_ SPP1 ( ortholog_one2one ) Dog_ SPP1 ( ortholog_one2one ) GuineaPig_ SPP1 ( ortholog_one2one ) Macaque_ SPP1 ( ortholog_one2one ) Mouse_ Spp1 ( ortholog_one2one ) Pig_ SPP1 ( ortholog_one2one ) Rat_ Spp1 ( ortholog_one2one ) Rabbit_ SPP1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Bone. Found in plasma. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 3CXD (X-ray 2.80A ) 3DSF (X-ray 2.80A ) |
| DBSNP | rs7435825 rs4660 |
| Subcellular location [CC] | Secreted. |
| Mouse PG classification | NA |
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