| Gene Information | |
|---|---|
| Gene Name | SPON1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 807 |
| Protein Names | Spondin-1 (F-spondin) (Vascular smooth muscle cell growth-promoting factor) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 950 ( ENSG00000262655 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q9HCB6 |
| Gene Card | SPON1 |
| Uniprot ID | Q9HCB6 |
| Pfam | PF02014; PF06468; PF19028; PF00090 |
| In ASD | no |
| Allosteric Prediction | no (-0.999765884) |
| Ortholog in Animals | Alpaca_ SPON1 ( ortholog_one2one ) Dog_ SPON1 ( ortholog_one2one ) GuineaPig_ SPON1 ( ortholog_one2one ) Macaque_ SPON1 ( ortholog_one2one ) Mouse_ Spon1 ( ortholog_one2one ) Pig_ SPON1 ( ortholog_one2one ) Rat_ Spon1 ( ortholog_one2one ) Rabbit_ SPON1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | SPON2, THSD7B, THSD7A |
| Tissue | NA |
| Tissue Specificity | Highest expression in lung, lower expression in brain, heart, kidney, liver and testis, and lowest expression in pancreas, skeletal muscle and ovary. Not expressed in spleen. {ECO:0000269|PubMed:11368520, ECO:0000269|PubMed:9872452}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2ZOT (X-ray 2.70A ) 2ZOU (X-ray 1.45A ) 3COO (X-ray 2.00A ) 3Q13 (X-ray 1.95A ) |
| DBSNP | NA |
| Subcellular location [CC] | Secreted, extracellular space, extracellular matrix {ECO:0000250}. |
| Mouse PG classification | NA |
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