Gene Information
Gene NameCST6
OrganismHomo sapiens (Human)
Gene Length98
Protein NamesCystatin-B (CPI-B) (Liver thiol proteinase inhibitor) (Stefin-B)
Target NameNA
Target TypeNA
Gene Age332 ( ENSG00000175315 )
Evolutionary StageEumetazoa
AlphaFoldDBP04080
Gene CardCSTB
Uniprot IDP04080
PfamPF00031
In ASDno
Allosteric Predictionno (-0.994588609)
Ortholog in AnimalsAlpaca_ CST6 ( ortholog_one2one )
Dog_ CST6 ( ortholog_one2one )
GuineaPig_ CST6 ( ortholog_one2one )
Macaque_ CST6 ( ortholog_one2one )
Mouse_ Cst6 ( ortholog_one2one )
Pig_ CST6 ( ortholog_one2one )
Rat_ Cst6 ( ortholog_one2one )
OhnologsCST3, CST4, CST5, CST2, CST1
ParalogsCST3, CST2, CST4, CST1, CST5, CST8, CST9, CST9L, CSTL1, CST11, CST7
Tissueskin, lower.leg.skin, suprapubic.skin
Tissue SpecificityNA
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 1STF  (X-ray  2.37A  2OCT  (X-ray  1.40A  4N6V  (X-ray  1.80A 
DBSNP rs74315443 
Subcellular location [CC]Cytoplasm {ECO:0000269|PubMed:11139332}. Nucleus {ECO:0000269|PubMed:11139332}.
Mouse PG classificationNA
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