Gene Information
Gene NameSPIR2
OrganismHomo sapiens (Human)
Gene Length714
Protein NamesProtein spire homolog 2 (Spir-2)
Target NameNA
Target TypeNA
Gene AgeNA
Evolutionary StageNA
AlphaFoldDBQ8WWL2
Gene CardSPIRE2
Uniprot IDQ8WWL2
PfamPF16474
In ASDno
Allosteric PredictionNA
Ortholog in AnimalsNA
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityNA
Pharmacological Animal ModelsNULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.066667(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 5JCY  (X-ray  1.80A 
DBSNP NA 
Subcellular location [CC]Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:Q8K1S6}. Cytoplasm, cytosol {ECO:0000250|UniProtKB:Q8K1S6}. Cell membrane {ECO:0000250|UniProtKB:Q8K1S6};
Peripheral membrane protein {ECO:0000250|UniProtKB:Q8K1S6};
Cytoplasmic side {ECO:0000250|UniProtKB:Q8K1S6}. Cytoplasmic vesicle membrane {ECO:0000250|UniProtKB:Q8K1S6};
Peripheral membrane protein {ECO:0000250|UniProtKB:Q8K1S6};
Cytoplasmic side {ECO:0000250|UniProtKB:Q8K1S6}. Note=Detected at the cleavage furrow during asymmetric oocyte division and polar body extrusion. {ECO:0000250|UniProtKB:Q8K1S6}.
Mouse PG classificationNA
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