| Gene Information | |
|---|---|
| Gene Name | SPINT2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 252 |
| Protein Names | Kunitz-type protease inhibitor 2 (Hepatocyte growth factor activator inhibitor type 2) (HAI-2) (Placental bikunin) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000167642 ) |
| Evolutionary Stage | Mammalia |
| AlphaFoldDB | O43291 |
| Gene Card | SPINT2 |
| Uniprot ID | O43291 |
| Pfam | PF00014 |
| In ASD | no |
| Allosteric Prediction | no (-0.506661036) |
| Ortholog in Animals | Alpaca_ SPINT2 ( ortholog_one2one ) Dog_ SPINT2 ( ortholog_one2one ) GuineaPig_ SPINT2 ( ortholog_one2one ) Macaque_ SPINT2 ( ortholog_one2one ) Mouse_ Spint2 ( ortholog_one2one ) Pig_ SPINT2 ( ortholog_one2one ) Rat_ Spint2 ( ortholog_one2one ) Rabbit_ SPINT2 ( ortholog_one2one ) |
| Ohnologs | SPINT1 |
| Paralogs | SPINT4, EPPIN, WFIKKN1, KIAA0319, TFPI, SPINT1, TFPI2, AMBP, WFIKKN2, WFDC8, LRP11, KIAA0319L, WFDC6 |
| Tissue | NA |
| Tissue Specificity | Expressed in placenta, kidney, pancreas, prostate, testis, thymus, and trachea. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | 4U32 (X-ray 1.65A ) |
| DBSNP | rs121908403 rs11548457 |
| Subcellular location [CC] | Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}. |
| Mouse PG classification | LPG |
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