| Gene Information | |
|---|---|
| Gene Name | SPINK2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 84 |
| Protein Names | Serine protease inhibitor Kazal-type 2 (Acrosin-trypsin inhibitor) (Epididymis tissue protein Li 172) (HUSI-II) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 132 ( ENSG00000128040 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | P20155 |
| Gene Card | SPINK2 |
| Uniprot ID | P20155 |
| Pfam | PF00050 |
| In ASD | no |
| Allosteric Prediction | no (-1.188793303) |
| Ortholog in Animals | Alpaca_ SPINK2 ( ortholog_one2one ) Macaque_ SPINK2 ( ortholog_one2one ) Mouse_ Spink2 ( ortholog_one2one ) Rat_ Spink2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | SPINK7, SPINK14, SPINK8, SPINK9, SPINK13 |
| Tissue | testis, epididymis, vas.deferens |
| Tissue Specificity | Expressed in epididymis (at protein level). {ECO:0000269|PubMed:20736409}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2JXD (NMR - ) 6KBR (X-ray 2.00A ) |
| DBSNP | NA |
| Subcellular location [CC] | Secreted {ECO:0000305}. Cytoplasmic vesicle, secretory vesicle, acrosome {ECO:0000269|PubMed:28554943}. |
| Mouse PG classification | NA |
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