Gene Information
Gene NameSNF1LK
OrganismHomo sapiens (Human)
Gene Length783
Protein NamesSerine/threonine-protein kinase SIK1 (EC 2.7.11.1) (Salt-inducible kinase 1) (SIK-1) (Serine/threonine-protein kinase SNF1-like kinase 1) (Serine/threonine-protein kinase SNF1LK)
Target NameNA
Target TypeNA
Gene AgeNA
Evolutionary StageNA
AlphaFoldDBP57059
Gene CardSIK1
Uniprot IDP57059
PfamPF00069
In ASDno
Allosteric PredictionNA
Ortholog in AnimalsNA
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityNA
Pharmacological Animal Models0.000730(Chimpanzee);0.001000(Mouse);NULL(Rat);NULL(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs3746951  rs45491503  rs786205159  rs34164089  rs430554  rs786205163  rs56386767  rs35596465 
Subcellular location [CC]Cytoplasm {ECO:0000269|PubMed:16306228, ECO:0000269|PubMed:29211348}. Nucleus {ECO:0000269|PubMed:16306228, ECO:0000269|PubMed:29211348}. Note=Locates to cytoplasm when inactive following cAMP-induced phosphorylation, probably by PKA (PubMed:29211348).
Mouse PG classificationNA
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