| Gene Information | |
|---|---|
| Gene Name | STRG |
| Organism | Homo sapiens (Human) |
| Gene Length | 384 |
| Protein Names | Probable G-protein coupled receptor 88 (Striatum-specific G-protein coupled receptor) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q9GZN0 |
| Gene Card | GPR88 |
| Uniprot ID | Q9GZN0 |
| Pfam | PF00001 |
| In ASD | yes |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed predominantly in the striatum. {ECO:0000269|PubMed:11056049}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 7EJX (EM 2.40A ) |
| DBSNP | rs2809819 rs3001995 |
| Subcellular location [CC] | Cell membrane {ECO:0000250|UniProtKB:Q9ESP4}; Multi-pass membrane protein {ECO:0000255}. Cytoplasm {ECO:0000250|UniProtKB:Q9ESP4}. Nucleus {ECO:0000250|UniProtKB:Q9ESP4}. Note=During cortical lamination, subcellular location shifts, on the day of birth, from expression at the plasma membrane and in the cytoplasm to the nuclei of neurons. This intranuclear localization remains throughout adulthood. {ECO:0000250|UniProtKB:Q9ESP4}. |
| Mouse PG classification | NA |
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