| Gene Information | |
|---|---|
| Gene Name | SLITRK2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 845 |
| Protein Names | SLIT and NTRK-like protein 2 |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000185985 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q9H156 |
| Gene Card | SLITRK2 |
| Uniprot ID | Q9H156 |
| Pfam | PF13855 |
| In ASD | no |
| Allosteric Prediction | no (-1.119366847) |
| Ortholog in Animals | Dog_ SLITRK2 ( ortholog_one2one ) Macaque_ SLITRK2 ( ortholog_one2one ) Mouse_ Slitrk2 ( ortholog_one2one ) Pig_ SLITRK2 ( ortholog_one2one ) Rat_ Slitrk2 ( ortholog_one2one ) Rabbit_ SLITRK2 ( ortholog_one2one ) |
| Ohnologs | SLITRK3, SLITRK5, SLITRK1, SLITRK6 |
| Paralogs | TLR9, LRRC70, LRFN2, LRFN5, SLITRK3, LRFN4, GP5, LINGO1, TPBGL, SLITRK6, LRFN1, LRRN1, SLITRK1, LRTM2, SLIT3, LRRN2, LRRN3, SLIT2, LRRC38, SLITRK4, LINGO2, SLIT1, SLITRK5, LRRC55, LRFN3 |
| Tissue | brain |
| Tissue Specificity | Expressed predominantly in the cerebral cortex of the brain but also at low levels in the spinal cord and medulla. Also expressed in some astrocytic brain tumors such as astrocytomas, oligodendrogliomas, glioblastomas, gangliogliomas and primitive neuroectodermal tumors. {ECO:0000269|PubMed:14557068}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs1402893590 rs1239180055 rs2295336 |
| Subcellular location [CC] | Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}. Cell membrane {ECO:0000269|PubMed:27812321}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |