| Gene Information | |
|---|---|
| Gene Name | SPG20 |
| Organism | Homo sapiens (Human) |
| Gene Length | 666 |
| Protein Names | Spartin (Spastic paraplegia 20 protein) (Trans-activated by hepatitis C virus core protein 1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q8N0X7 |
| Gene Card | SPART |
| Uniprot ID | Q8N0X7 |
| Pfam | PF06911 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Ubiquitously expressed, with highest levels of expression detected in adipose tissue. |
| Pharmacological Animal Models | 0.032198(Chimpanzee);0.029817(Mouse);0.001990(Rat);0.040000(Rabbit) |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2DL1 (NMR - ) 4U7I (X-ray 1.79A ) |
| DBSNP | rs1399213398 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:19580544}. Midbody {ECO:0000269|PubMed:20719964}. Note=Transiently associated with endosomes (PubMed:19580544). Colocalized with IST1 to the ends of Flemming bodies during cytokinesis (PubMed:20719964). {ECO:0000269|PubMed:19580544, ECO:0000269|PubMed:20719964}. |
| Mouse PG classification | HPG |
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