Gene Information
Gene NameSPECC1L
OrganismHomo sapiens (Human)
Gene Length1117
Protein NamesCytospin-A (Renal carcinoma antigen NY-REN-22) (Sperm antigen with calponin homology and coiled-coil domains 1-like) (SPECC1-like protein)
Target NameNA
Target TypeNA
Gene Age8 ( ENSG00000100014 )
Evolutionary StageEumetazoa
AlphaFoldDBQ69YQ0
Gene CardSPECC1L
Uniprot IDQ69YQ0
PfamPF00307
In ASDno
Allosteric Predictionno (-0.748975761)
Ortholog in AnimalsAlpaca_ SPECC1L ( ortholog_one2one )
Dog_ SPECC1L ( ortholog_one2one )
GuineaPig_ SPECC1L ( ortholog_one2one )
Macaque_ SPECC1L ( ortholog_one2one )
Mouse_ Specc1l ( ortholog_one2one )
Pig_ SPECC1L ( ortholog_one2one )
Rat_ Specc1l ( ortholog_one2one )
Rabbit_ SPECC1L ( ortholog_one2one )
OhnologsSPECC1
ParalogsSPECC1
TissueNA
Tissue SpecificityNA
Pharmacological Animal ModelsNULL(Chimpanzee);0.001000(Mouse);NULL(Rat);NULL(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs142144652  rs204710  rs786201030  rs387907108  rs5760340  rs6004132  rs11704759  rs204718  rs786201031 
Subcellular location [CC]Cytoplasm, cytoskeleton {ECO:0000269|PubMed:21703590}. Cytoplasm, cytoskeleton, spindle {ECO:0000269|PubMed:21703590}. Cell junction, gap junction {ECO:0000269|PubMed:21703590}. Note=Colocalizes with acetylated alpha-tubulin, gamma-tubulin and F-actin. Also observed in a ring around gamma-tubulin containing centrioles possibly in the microtubule organizing center.
Mouse PG classificationNA
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