| Gene Information | |
|---|---|
| Gene Name | SPECC1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1068 |
| Protein Names | Cytospin-B (Nuclear structure protein 5) (NSP5) (Sperm antigen HCMOGT-1) (Sperm antigen with calponin homology and coiled-coil domains 1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1064 ( ENSG00000128487 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q5M775 |
| Gene Card | SPECC1 |
| Uniprot ID | Q5M775 |
| Pfam | PF00307 |
| In ASD | no |
| Allosteric Prediction | no (-0.59519035) |
| Ortholog in Animals | Alpaca_ SPECC1 ( ortholog_one2one ) Dog_ SPECC1 ( ortholog_one2one ) GuineaPig_ SPECC1 ( ortholog_one2one ) Macaque_ SPECC1 ( ortholog_one2one ) Mouse_ Specc1 ( ortholog_one2one ) Pig_ SPECC1 ( ortholog_one2one ) Rat_ Specc1 ( ortholog_one2one ) Rabbit_ SPECC1 ( ortholog_one2one ) |
| Ohnologs | SPECC1L |
| Paralogs | SPECC1L |
| Tissue | NA |
| Tissue Specificity | Highly expressed in testis. Barely detectable in other tissues. Also highly expressed in some cancer cell lines. {ECO:0000269|PubMed:15602574}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs9908032 rs2703806 rs35835131 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:15602574}.; [Isoform 3]: Membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}.; [Isoform 4]: Membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}.; [Isoform 5]: Membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}. |
| Mouse PG classification | NA |
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