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Gene Information
Gene Name
MEN1
Organism
Homo sapiens (Human)
Gene Length
615
Protein Names
Menin
Target Name
NA
Target Type
NA
Gene Age
544 ( ENSG00000133895 )
Evolutionary Stage
Eukaryota
AlphaFoldDB
O00255
Gene Card
MEN1
Uniprot ID
O00255
Pfam
PF05053
In ASD
no
Allosteric Prediction
yes (0.861439444)
Ortholog in Animals
Alpaca_ MEN1 ( ortholog_one2one )
Dog_ MEN1 ( ortholog_one2one )
GuineaPig_ MEN1 ( ortholog_one2one )
Macaque_ MEN1 ( ortholog_one2one )
Mouse_ Men1 ( ortholog_one2one )
Pig_ MEN1 ( ortholog_one2one )
Rat_ Men1 ( ortholog_one2one )
Ohnologs
NA
Paralogs
NA
Tissue
NA
Tissue Specificity
Ubiquitous.
Pharmacological Animal Models
NA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB
3U84
(X-ray
2.50A
)
3U85
(X-ray
3.00A
)
3U86
(X-ray
2.84A
)
3U88
(X-ray
3.00A
)
4GPQ
(X-ray
1.46A
)
4GQ3
(X-ray
1.56A
)
4GQ4
(X-ray
1.27A
)
4GQ6
(X-ray
1.55A
)
4I80
(X-ray
3.10A
)
4OG3
(X-ray
2.01A
)
4OG4
(X-ray
1.45A
)
4OG5
(X-ray
1.63A
)
4OG6
(X-ray
1.49A
)
4OG7
(X-ray
2.08A
)
4OG8
(X-ray
1.53A
)
4X5Y
(X-ray
1.59A
)
4X5Z
(X-ray
1.86A
)
5DB0
(X-ray
1.50A
)
5DB1
(X-ray
1.86A
)
5DB2
(X-ray
1.54A
)
5DB3
(X-ray
1.71A
)
5DD9
(X-ray
1.62A
)
5DDA
(X-ray
1.83A
)
5DDB
(X-ray
1.54A
)
5DDC
(X-ray
1.62A
)
5DDD
(X-ray
2.14A
)
5DDE
(X-ray
1.78A
)
5DDF
(X-ray
1.66A
)
6B41
(X-ray
2.61A
)
6BXH
(X-ray
2.44A
)
6BXY
(X-ray
1.82A
)
6BY8
(X-ray
1.90A
)
6E1A
(X-ray
3.10A
)
6O5I
(X-ray
1.24A
)
6OPJ
(X-ray
1.50A
)
6PKC
(X-ray
1.90A
)
6S2K
(X-ray
3.10A
)
6WNH
(X-ray
2.10A
)
7M4T
(X-ray
2.74A
)
7OA9
(X-ray
2.10A
)
DBSNP
rs794728614
rs104894256
rs28931612
rs1592660101
rs1114167491
rs1389398299
rs104894263
rs1114167515
rs1114167543
rs1565648789
rs1941873896
rs794728648
rs1565648656
rs386134256
rs607969
rs1114167494
rs376872829
rs1555165811
rs1064793167
rs1941861451
rs1555165791
rs104894262
rs794728621
rs886039415
rs1057521110
rs1592649108
rs794728624
rs386134259
rs104894268
rs1941794175
rs1060499973
rs1114167493
rs1565645563
rs1114167495
rs1114167469
rs2071312
rs2071312
rs776561706
rs863224807
rs387906552
rs869025185
rs1555164707
rs794728627
rs1298484645
rs1446518998
rs104894264
rs104894264
rs386134249
rs1114167528
rs398124435
rs104894259
rs1941604532
rs745404679
rs2959656
rs1387157979
rs121913035
rs863224527
Subcellular location [CC]
Nucleus {ECO:0000269|PubMed:12874027}. Note=Concentrated in nuclear body-like structures. Relocates to the nuclear matrix upon gamma irradiation.
Mouse PG classification
HPG
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