| Gene Information | |
|---|---|
| Gene Name | UPF2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1272 |
| Protein Names | Regulator of nonsense transcripts 2 (Up-frameshift suppressor 2 homolog) (hUpf2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 18 ( ENSG00000151461 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9HAU5 |
| Gene Card | UPF2 |
| Uniprot ID | Q9HAU5 |
| Pfam | PF02854; PF04050 |
| In ASD | no |
| Allosteric Prediction | no (-0.861159018) |
| Ortholog in Animals | Alpaca_ UPF2 ( ortholog_one2one ) Dog_ UPF2 ( ortholog_one2one ) GuineaPig_ UPF2 ( ortholog_one2one ) Macaque_ UPF2 ( ortholog_one2one ) Mouse_ Upf2 ( ortholog_one2one ) Pig_ UPF2 ( ortholog_one2one ) Rat_ Upf2 ( ortholog_one2one ) Rabbit_ UPF2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Ubiquitous. {ECO:0000269|PubMed:11073994}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.033333(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1UW4 (X-ray 1.95A ) 2WJV (X-ray 2.85A ) 4CEK (X-ray 2.35A ) 4CEM (X-ray 2.60A ) 7NWU (X-ray 2.60A ) 7QG6 (X-ray 2.95A ) |
| DBSNP | rs7079388 |
| Subcellular location [CC] | Cytoplasm, perinuclear region {ECO:0000269|PubMed:11073994, ECO:0000269|PubMed:11113196, ECO:0000269|PubMed:11163187}. Cytoplasm {ECO:0000250|UniProtKB:A2AT37}. |
| Mouse PG classification | NA |
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