| Gene Information | |
|---|---|
| Gene Name | SART1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 800 |
| Protein Names | U4/U6.U5 tri-snRNP-associated protein 1 (SNU66 homolog) (hSnu66) (Squamous cell carcinoma antigen recognized by T-cells 1) (SART-1) (hSART-1) (U4/U6.U5 tri-snRNP-associated 110 kDa protein) (allergen Hom s 1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000175467 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | O43290 |
| Gene Card | SART1 |
| Uniprot ID | O43290 |
| Pfam | PF19252; PF03343 |
| In ASD | no |
| Allosteric Prediction | no (-0.912738936) |
| Ortholog in Animals | Alpaca_ SART1 ( ortholog_one2one ) Dog_ SART1 ( ortholog_one2one ) GuineaPig_ SART1 ( ortholog_one2one ) Macaque_ SART1 ( ortholog_one2one ) Mouse_ Sart1 ( ortholog_one2one ) Pig_ SART1 ( ortholog_one2one ) Rat_ Sart1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Ubiquitously expressed. {ECO:0000269|PubMed:9449708}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.197794(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 4PYU (X-ray 2.00A ) 5O9Z (EM 4.50A ) 6AHD (EM 3.80A ) 6QW6 (EM 2.92A ) 6QX9 (EM 3.28A ) |
| DBSNP | rs688862 rs35036096 rs660118 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:11350945, ECO:0000269|PubMed:9449708}. Note=Found in the nucleus of mitogen-activated peripheral blood mononuclear cells (PBMCs), tumor cells, or normal cell lines, but not in normal tissues except testis and fetal liver or in unstimulated PBMCs, suggesting preferential expression in proliferating cells. |
| Mouse PG classification | NA |
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