| Gene Information | |
|---|---|
| Gene Name | SPARCL1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 664 |
| Protein Names | SPARC-like protein 1 (High endothelial venule protein) (Hevin) (MAST 9) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 886 ( ENSG00000152583 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q14515 |
| Gene Card | SPARCL1 |
| Uniprot ID | Q14515 |
| Pfam | PF09289; PF00050; PF10591 |
| In ASD | no |
| Allosteric Prediction | no (-0.12201665) |
| Ortholog in Animals | Alpaca_ SPARCL1 ( ortholog_one2one ) Dog_ SPARCL1 ( ortholog_one2one ) GuineaPig_ SPARCL1 ( ortholog_one2one ) Macaque_ SPARCL1 ( ortholog_one2one ) Mouse_ Sparcl1 ( ortholog_one2one ) Pig_ SPARCL1 ( ortholog_one2one ) Rat_ Sparcl1 ( ortholog_one2one ) Rabbit_ SPARCL1 ( ortholog_one2one ) |
| Ohnologs | SPARC |
| Paralogs | SPARC |
| Tissue | NA |
| Tissue Specificity | Highly expressed in lymph node, brain, heart, lung, skeletal muscle, ovary, small intestine, and colon, with lower levels in placenta, pancreas, testis, spleen, and thymus, and no expression in kidney, liver, and peripheral blood leukocytes. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 7KBU (X-ray 2.27A ) |
| DBSNP | rs13051 rs1049544 rs1130643 |
| Subcellular location [CC] | Secreted, extracellular space, extracellular matrix {ECO:0000250}. |
| Mouse PG classification | NA |
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