| Gene Information | |
|---|---|
| Gene Name | SLIT3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1523 |
| Protein Names | Slit homolog 3 protein (Slit-3) (Multiple epidermal growth factor-like domains protein 5) (Multiple EGF-like domains protein 5) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000184347 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | O75094 |
| Gene Card | SLIT3 |
| Uniprot ID | O75094 |
| Pfam | PF00008; PF12661; PF02210; PF13855; PF01463; PF01462 |
| In ASD | no |
| Allosteric Prediction | no (-0.755087754) |
| Ortholog in Animals | Alpaca_ SLIT3 ( ortholog_one2one ) Dog_ SLIT3 ( ortholog_one2one ) GuineaPig_ SLIT3 ( ortholog_one2one ) Macaque_ SLIT3 ( ortholog_one2one ) Mouse_ Slit3 ( ortholog_one2one ) Pig_ SLIT3 ( ortholog_one2one ) Rat_ Slit3 ( ortholog_one2one ) Rabbit_ SLIT3 ( ortholog_one2one ) |
| Ohnologs | SLIT1, SLIT2 |
| Paralogs | TLR9, LRRC70, LRFN2, LRFN5, SLITRK3, LRFN4, GP5, SLITRK2, LINGO1, TPBGL, SLITRK6, LRFN1, LRRN1, SLITRK1, LRTM2, LRRN2, LRRN3, SLIT2, LRRC38, SLITRK4, LINGO2, SLIT1, SLITRK5, LRRC55, LRFN3 |
| Tissue | NA |
| Tissue Specificity | Predominantly expressed in thyroid. {ECO:0000269|PubMed:9813312}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001000(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs891921 rs2288792 rs10036727 rs36052924 rs2305993 rs10072243 |
| Subcellular location [CC] | Secreted {ECO:0000250}. |
| Mouse PG classification | NA |
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