Gene Information
Gene NameSPAT
OrganismHomo sapiens (Human)
Gene Length392
Protein NamesAlanine--glyoxylate aminotransferase (AGT) (EC 2.6.1.44) (Serine--pyruvate aminotransferase) (SPT) (EC 2.6.1.51)
Target NameNA
Target TypeNA
Gene AgeNA
Evolutionary StageNA
AlphaFoldDBP21549
Gene CardAGXT
Uniprot IDP21549
PfamPF00266
In ASDno
Allosteric PredictionNA
Ortholog in AnimalsNA
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityLiver.
Pharmacological Animal ModelsNULL(Chimpanzee);NULL(Mouse);0.026684(Rat);0.060606(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 1H0C  (X-ray  2.50A  1J04  (X-ray  2.60A  2YOB  (X-ray  1.90A  3R9A  (X-ray  2.35A  4CBR  (X-ray  2.30A  4CBS  (X-ray  2.30A  4I8A  (X-ray  2.90A  4KXK  (X-ray  2.90A  4KYO  (X-ray  2.20A  5F9S  (X-ray  1.70A  5HHY  (X-ray  1.70A  5LUC  (X-ray  1.80A  5OFY  (X-ray  2.80A  5OG0  (X-ray  2.50A  6RV0  (X-ray  2.70A  6RV1  (X-ray  3.00A  7NS7  (X-ray  2.20A 
DBSNP rs115014558  rs34116584  rs34885252  rs180177157  rs180177168  rs121908523  rs180177168  rs180177173  rs121908522  rs180177185  rs180177197  rs796052061  rs180177207  rs180177222  rs121908524  rs180177223  rs121908530  rs180177225  rs180177227  rs180177227  rs180177227  rs180177230  rs121908529  rs180177231  rs180177236  rs180177238  rs180177239  rs180177244  rs180177246  rs536352238  rs121908520  rs180177253  rs121908526  rs121908527  rs121908527  rs180177258  rs121908525  rs180177264  rs180177277  rs140992177  rs73106685  rs180177289  rs180177290  rs13408961  rs180177291  rs180177293  rs115057148  rs180177155  rs4426527  rs180177156 
Subcellular location [CC]Peroxisome {ECO:0000269|PubMed:10960483, ECO:0000269|PubMed:12777626, ECO:0000269|PubMed:1703535, ECO:0000269|PubMed:23229545, ECO:0000269|PubMed:24055001, ECO:0000269|PubMed:26149463}.
Mouse PG classificationNA
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