| Gene Information | |
|---|---|
| Gene Name | SPAG4L |
| Organism | Homo sapiens (Human) |
| Gene Length | 379 |
| Protein Names | SUN domain-containing protein 5 (Sad1 and UNC84 domain-containing protein 5) (Sperm-associated antigen 4-like protein) (Testis and spermatogenesis-related gene 4 protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q8TC36 |
| Gene Card | SUN5 |
| Uniprot ID | Q8TC36 |
| Pfam | PF07738 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Sperm (at protein level) (PubMed:27640305). Widely expressed (PubMed:12621555). Conflictingly shown to be specifically expressed in testis (PubMed:21711156). {ECO:0000269|PubMed:12621555, ECO:0000269|PubMed:21711156, ECO:0000269|PubMed:27640305}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs3746387 rs1133358 rs35216976 rs886041023 rs17123951 rs886041024 rs756459525 rs758335571 rs754130052 |
| Subcellular location [CC] | Nucleus inner membrane {ECO:0000305|PubMed:27640305}; Single-pass membrane protein {ECO:0000250|UniProtKB:Q9DA32}. Golgi apparatus {ECO:0000250|UniProtKB:Q9DA32}. Note=During spermiogenesis, traffics through the Golgi apparatus before reaching the round spermatid inner membrane of the nuclear envelope and later migrates to the coupling apparatus of the sperm during sperm head elongation and differentiation. In mature spermatozoa, is localized to the coupling apparatus of the sperm head and tail in the implementation fossa. {ECO:0000305|PubMed:27640305}. |
| Mouse PG classification | NA |
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