Gene Information
Gene NameSRP54
OrganismHomo sapiens (Human)
Gene Length504
Protein NamesSignal recognition particle 54 kDa protein (SRP54) (EC 3.6.5.-)
Target NameNA
Target TypeNA
Gene Age>4290 ( ENSG00000100883 )
Evolutionary StageCellular_organisms
AlphaFoldDBP61011
Gene CardSRP54
Uniprot IDP61011
PfamPF00448; PF02881; PF02978
In ASDno
Allosteric Predictionno (-0.788159505)
Ortholog in AnimalsAlpaca_ SRP54 ( ortholog_one2one )
Alpaca_ FAM177A1 ( ortholog_one2one )
Dog_ SRP54 ( ortholog_one2one )
GuineaPig_ SRP54 ( ortholog_one2one )
Macaque_ SRP54 ( ortholog_one2one )
Mouse_ Srp54b ( ortholog_one2many )
Mouse_ Srp54c ( ortholog_one2many )
Mouse_ Srp54a ( ortholog_one2many )
Pig_ SRP54 ( ortholog_one2one )
Rat_ Srp54a ( ortholog_one2one )
Rabbit_ SRP54 ( ortholog_one2one )
OhnologsNA
ParalogsSRPRA
TissueNA
Tissue SpecificityNA
Pharmacological Animal ModelsNULL(Chimpanzee);NULL(Mouse);0.059684(Rat);0.044205(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 1MFQ  (X-ray  3.10A  1QB2  (X-ray  2.10A  5L3Q  (X-ray  3.20A  6Y2Z  (X-ray  2.15A  6Y30  (X-ray  2.65A  6Y31  (X-ray  4.00A  6Y32  (X-ray  2.60A  7NFX  (EM  3.20A  7QWQ  (EM  2.83A 
DBSNP NA 
Subcellular location [CC]Nucleus speckle {ECO:0000269|PubMed:14729963}. Cytoplasm {ECO:0000269|PubMed:14729963, ECO:0000269|PubMed:29914977}. Endoplasmic reticulum {ECO:0000269|PubMed:29914977}.
Mouse PG classificationNA
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