| Gene Information | |
|---|---|
| Gene Name | KCNN1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 543 |
| Protein Names | Small conductance calcium-activated potassium channel protein 1 (SK1) (SKCa 1) (SKCa1) (KCa2.1) |
| Target Name | calcium-activated potassium channel kca2.1 |
| Target Type | Clinical trial target |
| Gene Age | 810 ( ENSG00000105642 ) |
| Evolutionary Stage | Mammalia |
| AlphaFoldDB | Q92952 |
| Gene Card | KCNN1 |
| Uniprot ID | Q92952 |
| Pfam | PF02888; PF07885; PF03530 |
| In ASD | yes |
| Allosteric Prediction | yes (0.965840503) |
| Ortholog in Animals | Alpaca_ KCNN1 ( ortholog_one2one ) Dog_ KCNN1 ( ortholog_one2one ) GuineaPig_ KCNN1 ( ortholog_one2one ) Macaque_ KCNN1 ( ortholog_one2one ) Mouse_ Kcnn1 ( ortholog_one2one ) Pig_ KCNN1 ( ortholog_one2one ) Rat_ Kcnn1 ( ortholog_one2one ) |
| Ohnologs | KCNN2, KCNN3 |
| Paralogs | KCNN3, KCNN4, KCNN2 |
| Tissue | amygdala, cerebral.cortex, hippocampus |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Membrane; Multi-pass membrane protein. |
| Mouse PG classification | NA |
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