| Gene Information | |
|---|---|
| Gene Name | SNX8 |
| Organism | Homo sapiens (Human) |
| Gene Length | 465 |
| Protein Names | Sorting nexin-8 |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1292 ( ENSG00000106266 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9Y5X2 |
| Gene Card | SNX8 |
| Uniprot ID | Q9Y5X2 |
| Pfam | PF00787; PF19566 |
| In ASD | no |
| Allosteric Prediction | no (-0.823931349) |
| Ortholog in Animals | Alpaca_ SNX8 ( ortholog_one2one ) Dog_ SNX8 ( ortholog_one2one ) GuineaPig_ SNX8 ( ortholog_one2one ) Macaque_ SNX8 ( ortholog_one2one ) Mouse_ Snx8 ( ortholog_one2one ) Pig_ SNX8 ( ortholog_one2one ) Rat_ Snx8 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | SNX5, SNX6, SNX2, SNX18, SNX7, SNX33, SNX10, SNX4, SNX1, SNX11, SNX12, SNX3, SNX30, SNX32, SNX9 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001000(Rat);0.05(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Early endosome membrane {ECO:0000269|PubMed:19782049}; Peripheral membrane protein {ECO:0000269|PubMed:19782049}; Cytoplasmic side {ECO:0000269|PubMed:19782049}. Note=Colocalizes with retromer components. |
| Mouse PG classification | NA |
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