| Gene Information | |
|---|---|
| Gene Name | SPACA7 |
| Organism | Homo sapiens (Human) |
| Gene Length | 195 |
| Protein Names | Sperm acrosome-associated protein 7 |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 382 ( ENSG00000153498 ) 3 ( ENSG00000275865 ) |
| Evolutionary Stage | Mammalia |
| AlphaFoldDB | Q96KW9 |
| Gene Card | SPACA7 |
| Uniprot ID | Q96KW9 |
| Pfam | PF15307 |
| In ASD | no |
| Allosteric Prediction | no (-1.110402283) |
| Ortholog in Animals | Alpaca_ SPACA7 ( ortholog_one2one ) Dog_ SPACA7 ( ortholog_one2one ) Macaque_ SPACA7 ( ortholog_one2one ) Mouse_ Spaca7 ( ortholog_one2one ) Rat_ Spaca7 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | testis |
| Tissue Specificity | Expressed in spermatozoa (at protein level) (PubMed:22495889). {ECO:0000269|PubMed:22495889}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs376712879 rs10816 |
| Subcellular location [CC] | Secreted {ECO:0000250|UniProtKB:Q9D2S4}. Cytoplasmic vesicle, secretory vesicle, acrosome {ECO:0000269|PubMed:22495889}. Cytoplasmic vesicle, secretory vesicle, acrosome lumen {ECO:0000250|UniProtKB:Q9D2S4}. Note=Localized in perinuclear pro-acrosomal granules in round spermatides. Localized between the inner and outer acrosomal membranes (matrix or lumen) in spermatozoa. Secreted during acrosome exocytosis. {ECO:0000250|UniProtKB:Q9D2S4}. |
| Mouse PG classification | NA |
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