Gene Information
Gene NameSPAAR
OrganismHomo sapiens (Human)
Gene Length90
Protein NamesSmall regulatory polypeptide of amino acid response
Target NameNA
Target TypeNA
Gene Age680 ( ENSG00000235387 )
Evolutionary StageNA
AlphaFoldDBA0A1B0GVQ0
Gene CardSPAAR
Uniprot IDA0A1B0GVQ0
PfamNA
In ASDno
Allosteric Predictionno (-1.356980103)
Ortholog in AnimalsAlpaca_ SPAAR ( ortholog_one2one )
Macaque_ SPAAR ( ortholog_one2one )
Mouse_ Spaar ( ortholog_one2one )
Pig_ SPAAR ( ortholog_one2one )
OhnologsNA
ParalogsNA
Tissueadipose.tissue, testis
Tissue SpecificityHighly expressed in lung, heart and skeletal muscle. {ECO:0000269|PubMed:28024296}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP NA 
Subcellular location [CC]Late endosome membrane {ECO:0000269|PubMed:28024296};
Single-pass membrane protein {ECO:0000305|PubMed:28024296}. Lysosome membrane {ECO:0000269|PubMed:28024296};
Single-pass membrane protein {ECO:0000305|PubMed:28024296}.
Mouse PG classificationNA
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