| Gene Information | |
|---|---|
| Gene Name | SPA1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1042 |
| Protein Names | Signal-induced proliferation-associated protein 1 (Sipa-1) (GTPase-activating protein Spa-1) (p130 SPA-1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q96FS4 |
| Gene Card | SIPA1 |
| Uniprot ID | Q96FS4 |
| Pfam | PF00595; PF02145 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed in fetal as well as in adult tissues. Expressed abundantly in the lymphoid tissues such as thymus, spleen and peripheral blood lymphocytes and also shows a significant expression in the spinal cord. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs35045265 rs3741379 rs34912782 rs3741378 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:9346962}. Cytoplasm, perinuclear region {ECO:0000269|PubMed:9346962}. Endomembrane system; Peripheral membrane protein {ECO:0000269|PubMed:9346962}. Note=Mostly localized in the perinuclear membraneous region. {ECO:0000269|PubMed:9346962}. |
| Mouse PG classification | NA |
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