Gene Information
Gene NameSP7
OrganismHomo sapiens (Human)
Gene Length431
Protein NamesTranscription factor Sp7 (Zinc finger protein osterix)
Target NameNA
Target TypeNA
Gene Age950 ( ENSG00000170374 )
Evolutionary StageVertebrata
AlphaFoldDBQ8TDD2
Gene CardSP7
Uniprot IDQ8TDD2
PfamPF00096
In ASDno
Allosteric Predictionno (-0.619219449)
Ortholog in AnimalsAlpaca_ SP7 ( ortholog_one2one )
GuineaPig_ SP7 ( ortholog_one2one )
Macaque_ SP7 ( ortholog_one2one )
Mouse_ Sp7 ( ortholog_one2one )
Pig_ SP7 ( ortholog_one2one )
Rat_ Sp7 ( ortholog_one2one )
Rabbit_ SP7 ( ortholog_one2one )
OhnologsSP6, SP8, SP9
ParalogsKLF17, KLF11, KLF18, SP8, KLF15, KLF13, SP9, KLF16, KLF5, KLF12, KLF7, KLF3, KLF2, SP5, SP6, KLF8, KLF1, KLF14, KLF6, KLF10, KLF4, KLF9
TissueNA
Tissue SpecificityRestricted to bone-derived cell. {ECO:0000269|PubMed:15474293}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP NA 
Subcellular location [CC]Nucleus {ECO:0000250|UniProtKB:Q8VI67}.
Mouse PG classificationNA
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