Gene Information
Gene NameSP6
OrganismHomo sapiens (Human)
Gene Length376
Protein NamesTranscription factor Sp6 (Krueppel-like factor 14)
Target NameNA
Target TypeNA
Gene Age950 ( ENSG00000189120 )
Evolutionary StageOpisthokonta
AlphaFoldDBQ3SY56
Gene CardSP6
Uniprot IDQ3SY56
PfamPF00096
In ASDno
Allosteric Predictionno (-1.214201632)
Ortholog in AnimalsAlpaca_ SP6 ( ortholog_one2one )
Dog_ SP6 ( ortholog_one2one )
GuineaPig_ SP6 ( ortholog_one2one )
Macaque_ SP6 ( ortholog_one2one )
Mouse_ Sp6 ( ortholog_one2one )
Pig_ SP6 ( ortholog_one2one )
Rat_ Sp6 ( ortholog_one2one )
Rabbit_ SP6 ( ortholog_one2one )
OhnologsSP8, SP7, SP5, SP9
ParalogsKLF17, KLF11, KLF18, SP8, KLF15, KLF13, SP9, SP7, KLF16, KLF5, KLF12, KLF7, KLF3, KLF2, SP5, KLF8, KLF1, KLF14, KLF6, KLF10, KLF4, KLF9
Tissueplacenta
Tissue SpecificityUbiquitous.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs34309518 
Subcellular location [CC]Nucleus {ECO:0000250}.
Mouse PG classificationNA
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