| Gene Information | |
|---|---|
| Gene Name | SP110 |
| Organism | Homo sapiens (Human) |
| Gene Length | 689 |
| Protein Names | Sp110 nuclear body protein (Interferon-induced protein 41/75) (Speckled 110 kDa) (Transcriptional coactivator Sp110) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000135899 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q9HB58 |
| Gene Card | SP110 |
| Uniprot ID | Q9HB58 |
| Pfam | PF03172; PF01342 |
| In ASD | no |
| Allosteric Prediction | no (-0.800198203) |
| Ortholog in Animals | Alpaca_ SP110 ( ortholog_one2one ) Dog_ SP110 ( ortholog_one2one ) Macaque_ SP110 ( ortholog_one2one ) Mouse_ Sp110 ( ortholog_one2many ) Pig_ SP110 ( ortholog_one2one ) Rat_ Sp110 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | SP140, HMGB2, UBTF, TOX4, UBTFL1, HMGB1P1, HMGB1, SP100, SMARCE1, HMGB3, HMG20A, TFAM, HMG20B, SSRP1, TOX2, TOX, HMGB4, SP140L, HMGXB4, TOX3 |
| Tissue | NA |
| Tissue Specificity | Highly expressed in peripheral blood leukocytes and spleen. Detected at intermediate levels in thymus, prostate, testis, ovary, small intestine and colon, and at low levels in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs200067258 rs1129411 rs11556887 rs41552315 rs28930679 rs9061 rs1063154 rs1047254 rs3769838 rs1129425 rs1365776 rs59573011 rs3948464 rs1135791 rs3948463 |
| Subcellular location [CC] | Nucleus {ECO:0000255|PROSITE-ProRule:PRU00185, ECO:0000255|PROSITE-ProRule:PRU00747, ECO:0000269|PubMed:10913195}. Note=Found in the nuclear body. |
| Mouse PG classification | NA |
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