| Gene Information | |
|---|---|
| Gene Name | SP1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 189 |
| Protein Names | DAN domain family member 5 (Cerberus-like protein 2) (Cerl-2) (Cysteine knot superfamily 1, BMP antagonist 3) (Gremlin-3) |
| Target Name | transcription factor sp1 |
| Target Type | Clinical trial target |
| Gene Age | 645 ( ENSG00000185591 ) |
| Evolutionary Stage | Opisthokonta |
| AlphaFoldDB | Q8N907 |
| Gene Card | DAND5 |
| Uniprot ID | Q8N907 |
| Pfam | PF03045 |
| In ASD | no |
| Allosteric Prediction | yes (1.1301577) |
| Ortholog in Animals | Alpaca_ SP1 ( ortholog_one2one ) Dog_ SP1 ( ortholog_one2one ) GuineaPig_ SP1 ( ortholog_one2one ) Macaque_ SP1 ( ortholog_one2one ) Mouse_ Sp1 ( ortholog_one2one ) Pig_ SP1 ( ortholog_one2one ) Rat_ Sp1 ( ortholog_one2one ) Rabbit_ SP1 ( ortholog_one2one ) |
| Ohnologs | SP2, SP4, SP3 |
| Paralogs | SP3, SP2, SP4 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Secreted {ECO:0000305}. |
| Mouse PG classification | NA |
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