| Gene Information | |
|---|---|
| Gene Name | SOX17 |
| Organism | Homo sapiens (Human) |
| Gene Length | 414 |
| Protein Names | Transcription factor SOX-17 |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 950 ( ENSG00000164736 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q9H6I2 |
| Gene Card | SOX17 |
| Uniprot ID | Q9H6I2 |
| Pfam | PF00505; PF12067 |
| In ASD | no |
| Allosteric Prediction | no (-0.852187981) |
| Ortholog in Animals | Alpaca_ SOX17 ( ortholog_one2one ) Dog_ SOX17 ( ortholog_one2one ) GuineaPig_ SOX17 ( ortholog_one2one ) Macaque_ SOX17 ( ortholog_one2one ) Mouse_ Sox17 ( ortholog_one2one ) Pig_ SOX17 ( ortholog_one2one ) Rat_ Sox17 ( ortholog_one2one ) |
| Ohnologs | SOX7, SOX18 |
| Paralogs | SOX12, SOX13, SOX30, CFAP65, SOX21, SOX8, SOX7, SOX5, SOX14, SOX6, SOX9, SRY, SOX10, SOX1, SOX4, SOX18, SOX11, SOX3, SOX2, SOX15 |
| Tissue | NA |
| Tissue Specificity | Expressed in adult heart, lung, spleen, testis, ovary, placenta, fetal lung, and kidney. In normal gastrointestinal tract, it is preferentially expressed in esophagus, stomach and small intestine than in colon and rectum. {ECO:0000269|PubMed:11786926}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2YUL (NMR - ) 4A3N (X-ray 2.40A ) |
| DBSNP | rs189384157 rs267607082 rs267607083 |
| Subcellular location [CC] | Nucleus {ECO:0000255|PROSITE-ProRule:PRU00267}. |
| Mouse PG classification | LPG |
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