| Gene Information | |
|---|---|
| Gene Name | TSPAN33 |
| Organism | Homo sapiens (Human) |
| Gene Length | 283 |
| Protein Names | Tetraspanin-33 (Tspan-33) (Penumbra) (hPen) (Proerythroblast new membrane) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000158457 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q86UF1 |
| Gene Card | TSPAN33 |
| Uniprot ID | Q86UF1 |
| Pfam | PF00335 |
| In ASD | no |
| Allosteric Prediction | no (-0.998467203) |
| Ortholog in Animals | Alpaca_ TSPAN33 ( ortholog_one2one ) Alpaca_ TSPAN33 ( ortholog_one2many ) Dog_ TSPAN33 ( ortholog_one2one ) GuineaPig_ TSPAN33 ( ortholog_one2one ) Macaque_ TSPAN33 ( ortholog_one2one ) Mouse_ Tspan33 ( ortholog_one2one ) Pig_ TSPAN33 ( ortholog_one2one ) Rat_ Tspan33 ( ortholog_one2one ) Rabbit_ TSPAN33 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | ROM1, TSPAN12, CD63, TSPAN10, CD9, TSPAN6, TSPAN5, CD37, CD151, TSPAN4, TSPAN1, TSPAN31, UPK1A, TSPAN17, TSPAN11, TSPAN32, TSPAN8, TSPAN13, TSPAN2, CD53, TSPAN9, TSPAN18, CD81, CD82, TSPAN16, TSPAN19, TSPAN7, UPK1B, TSPAN3, TSPAN14, TSPAN15, PRPH2 |
| Tissue | NA |
| Tissue Specificity | Predominantly expressed in erythroblasts. {ECO:0000269|PubMed:17158226}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:26686862}; Multi-pass membrane protein {ECO:0000305}. Cell junction, adherens junction {ECO:0000269|PubMed:30463011}. Cytoplasm {ECO:0000269|PubMed:30463011}. Note=Is localized to zonula adherens by PLEKHA7 by a PDZD11-dependent interaction. {ECO:0000269|PubMed:30463011}. |
| Mouse PG classification | NA |
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