| Gene Information | |
|---|---|
| Gene Name | SOS2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1332 |
| Protein Names | Son of sevenless homolog 2 (SOS-2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000100485 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q07890 |
| Gene Card | SOS2 |
| Uniprot ID | Q07890 |
| Pfam | PF00169; PF00617; PF00618; PF00621 |
| In ASD | yes |
| Allosteric Prediction | yes (0.619014656) |
| Ortholog in Animals | Alpaca_ SOS2 ( ortholog_one2one ) Dog_ SOS2 ( ortholog_one2one ) GuineaPig_ SOS2 ( ortholog_one2one ) Macaque_ SOS2 ( ortholog_one2one ) Mouse_ Sos2 ( ortholog_one2one ) Pig_ SOS2 ( ortholog_one2one ) Rat_ Sos2 ( ortholog_one2one ) Rabbit_ SOS2 ( ortholog_one2one ) |
| Ohnologs | SOS1 |
| Paralogs | RALGDS, RASGEF1A, RASGRF2, RASGRP3, RAPGEF3, RAPGEF6, RASGRF1, RAPGEF2, RGL1, RAPGEF1, RASGEF1B, RASGRP2, RGL2, SOS1, RGL3, RALGPS1, RALGPS2, RAPGEF4, RGL4, RASGRP4, RAPGEFL1, RAPGEF5, RASGRP1, RASGEF1C |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.002657(Rat);0.033333(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 6EIE (X-ray 2.72A ) |
| DBSNP | rs797045167 rs373233749 rs869320687 rs768547025 rs17122201 rs8010237 rs34139502 rs200387871 rs1442962879 |
| Subcellular location [CC] | NA |
| Mouse PG classification | NA |
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