| Gene Information | |
|---|---|
| Gene Name | PRKD1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 912 |
| Protein Names | Serine/threonine-protein kinase D1 (EC 2.7.11.13) (Protein kinase C mu type) (Protein kinase D) (nPKC-D1) (nPKC-mu) |
| Target Name | serine/threonine-protein kinase d1 |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000184304 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q15139 |
| Gene Card | PRKD1 |
| Uniprot ID | Q15139 |
| Pfam | PF00130; PF00169; PF00069 |
| In ASD | no |
| Allosteric Prediction | yes (0.741169616) |
| Ortholog in Animals | Alpaca_ PRKD1 ( ortholog_one2one ) GuineaPig_ PRKD1 ( ortholog_one2one ) Macaque_ PRKD1 ( ortholog_one2one ) Mouse_ Prkd1 ( ortholog_one2one ) Pig_ PRKD1 ( ortholog_one2one ) Rat_ Prkd1 ( ortholog_one2one ) Rabbit_ PRKD1 ( ortholog_one2one ) |
| Ohnologs | PRKD2, PRKD3 |
| Paralogs | PRKD2, PRKD3 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.04(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs1383618278 rs1057519636 rs55852813 rs1057519635 rs34588699 rs11161065 rs45582934 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:18076381}. Cell membrane {ECO:0000269|PubMed:18076381}. Golgi apparatus, trans-Golgi network {ECO:0000250|UniProtKB:Q62101}. Note=Translocation to the cell membrane is required for kinase activation. |
| Mouse PG classification | NA |
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