| Gene Information | |
|---|---|
| Gene Name | SFTA2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 78 |
| Protein Names | Surfactant-associated protein 2 (Surfactant-associated protein G) (SP-G) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 454 ( ENSG00000196260 ) 3 ( ENSG00000206465 ) 3 ( ENSG00000224246 ) 3 ( ENSG00000225454 ) 3 ( ENSG00000230072 ) 3 ( ENSG00000237814 ) |
| Evolutionary Stage | Mammalia |
| AlphaFoldDB | Q6UW10 |
| Gene Card | SFTA2 |
| Uniprot ID | Q6UW10 |
| Pfam | PF15210 |
| In ASD | no |
| Allosteric Prediction | no (-1.869602469) |
| Ortholog in Animals | Alpaca_ SFTA2 ( ortholog_one2one ) Dog_ SFTA2 ( ortholog_one2one ) Macaque_ SFTA2 ( ortholog_one2one ) Pig_ SFTA2 ( ortholog_one2one ) Rabbit_ SFTA2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | lung |
| Tissue Specificity | Predominantly expressed in lung, where it is detected in type II pneumocytes in the alveolus, and in nonciliated epithelium in bronchioli (at protein level). Also detected at lower levels in cervix, esophagus, stomach, testis and kidney. {ECO:0000269|PubMed:22768197}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs3131787 |
| Subcellular location [CC] | Secreted {ECO:0000305|PubMed:22768197}. Cytoplasmic vesicle, secretory vesicle {ECO:0000269|PubMed:22768197}. Golgi apparatus {ECO:0000269|PubMed:22768197}. |
| Mouse PG classification | NA |
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