| Gene Information | |
|---|---|
| Gene Name | SOD2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 222 |
| Protein Names | Superoxide dismutase [Mn], mitochondrial (EC 1.15.1.1) |
| Target Name | superoxide dismutase mn |
| Target Type | Clinical trial target |
| Gene Age | NA |
| Evolutionary Stage | Cellular_organisms |
| AlphaFoldDB | P04179 |
| Gene Card | SOD2 |
| Uniprot ID | P04179 |
| Pfam | PF02777; PF00081 |
| In ASD | no |
| Allosteric Prediction | yes (0.487580029) |
| Ortholog in Animals | Alpaca_ SOD2 ( ortholog_one2one ) Dog_ SOD2 ( ortholog_one2many ) GuineaPig_ SOD2 ( ortholog_one2one ) Macaque_ SOD2 ( ortholog_one2one ) Mouse_ Sod2 ( ortholog_one2one ) Pig_ SOD2 ( ortholog_one2one ) Rat_ Sod2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.003411(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1AP5 (X-ray 2.20A ) 1AP6 (X-ray 1.90A ) 1EM1 (X-ray 2.13A ) 1JA8 (X-ray 2.12A ) 1LUV (X-ray 1.85A ) 1LUW (X-ray 2.30A ) 1MSD (X-ray 3.20A ) 1N0J (X-ray 2.20A ) 1N0N (X-ray 1.82A ) 1PL4 (X-ray 1.47A ) 1PM9 (X-ray 1.70A ) 1QNM (X-ray 2.30A ) 1SZX (X-ray 1.95A ) 1VAR (X-ray 2.50A ) 1XDC (X-ray 1.85A ) 1XIL (X-ray 1.53A ) 1ZSP (X-ray 1.90A ) 1ZTE (X-ray 1.85A ) 1ZUQ (X-ray 2.00A ) 2ADP (X-ray 2.40A ) 2ADQ (X-ray 2.40A ) 2GDS (X-ray 2.30A ) 2P4K (X-ray 1.48A ) 2QKA (X-ray 2.20A ) 2QKC (X-ray 2.30A ) 3C3S (X-ray 2.50A ) 3C3T (X-ray 2.20A ) 5GXO (X-ray 2.30A ) 5T30 (X-ray 1.77A ) 5VF9 (X-ray 1.82A ) 7KKS (Neutron 2.20A ) 7KKU (X-ray 2.02A ) 7KKW (Neutron 2.30A ) 7KLB (X-ray 2.16A ) |
| DBSNP | rs5746096 rs4880 rs5746097 rs4987023 rs1141718 rs5746129 |
| Subcellular location [CC] | Mitochondrion matrix. |
| Mouse PG classification | NA |
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